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The safety of food-grade titanium dioxide, or E171, lies in its ultrafine particle size. These particles are too small to be absorbed by the human body, passing through the digestive system without causing harm. Extensive research has been conducted to confirm this, with studies showing no evidence of genotoxicity or carcinogenicity. However, recent concerns about potential effects from nano-sized particles have led to ongoing evaluations However, recent concerns about potential effects from nano-sized particles have led to ongoing evaluations However, recent concerns about potential effects from nano-sized particles have led to ongoing evaluations However, recent concerns about potential effects from nano-sized particles have led to ongoing evaluationsfood safe titanium dioxide.

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While IARC listed titanium dioxide as “possibly carcinogenic to humans,” they also add that “there is inadequate evidence in humans for the carcinogenicity of titanium dioxide.” Of the four human studies that they reviewed, only one showed a potential risk for occupational workers inhaling titanium dioxide particles and lung cancer, while the other three showed no risk for cancer at all. And it’s key to note that IARC did not assess the effects of titanium dioxide found in foods.

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